Quad core MP w/ 8800GT.. 1920x1080 res full screen.. Snow w/ COG 8.0. The only thing that doesn't work is AA, but meh - no big deal. Couple artificats here or there and the full screen haze is a bit different (probably earlier shader or compatibility), but pretty solid 60+ fps.
The only thing I really need to do is fix the mouse - the inconsistent acceleration curve OSX uses really makes twitch gaming difficult.