Hi. I should note that this works on a build with an AMD Ryzen CPU with AMD graphics (Radeon RX 570). Do NOT install proprietary display drivers from AMD; just use the drivers provided when you install CentOS 8. I suggest this based on experience. Regarding the actual install, first make sure your system is up to date. Then, run these commands:
1) sudo dnf groupinstall "Development Tools"
2) sudo dnf install alsa-plugins-pulseaudio.i686 glibc-devel.i686 glibc-devel libgcc.i686 libX11-devel.i686 freetype-devel.i686 libXcursor-devel.i686 libXi-devel.i686 libXext-devel.i686 libXxf86vm-devel.i686 libXrandr-devel.i686 libXinerama-devel.i686 mesa-libGLU-devel.i686 mesa-libOSMesa-devel.i686 libXrender-devel.i686 libpcap-devel.i686 ncurses-devel.i686 lcms2-devel.i686 zlib-devel.i686 libv4l-devel.i686 libgphoto2-devel.i686 cups-devel.i686 libxml2-devel.i686 openldap-devel.i686 gnutls-devel.i686 libpng-devel.i686 flac-libs.i686 json-c.i686 libICE.i686 libSM.i686 libXtst.i686 libasyncns.i686 libedit.i686 liberation-narrow-fonts.noarch libieee1284.i686 libogg.i686 libsndfile.i686 libuuid.i686 libva.i686 libvorbis.i686 libwayland-client.i686 libwayland-server.i686 llvm-libs.i686 mesa-dri-drivers.i686 mesa-filesystem.i686 mesa-libEGL.i686 mesa-libgbm.i686 ocl-icd.i686 pulseaudio-libs.i686 sane-backends-libs.i686 unixODBC.i686 samba-common-tools.x86_64 samba-libs.x86_64 samba-winbind.x86_64 samba-winbind-clients.x86_64 samba-winbind-modules.x86_64 mesa-libGL-devel.i686 fontconfig-devel.i686 libXcomposite-devel.i686 libtiff-devel.i686 openal-soft-devel.i686 alsa-lib-devel.i686 gsm-devel.i686 libjpeg-turbo-devel.i686 pulseaudio-libs-devel.i686 pulseaudio-libs-devel gtk3-devel.i686 libattr-devel.i686 libva-devel.i686 libexif-devel.i686 libexif.i686 glib2-devel.i686 mpg123-devel.i686 mpg123-devel.x86_64 libcom_err-devel.i686 libcom_err-devel.x86_64 mesa-libGL-devel libv4l.i686 fontconfig.i686 libXcomposite.i686 libXinerama.i686 libgphoto2.i686 libxml2.i686 libxslt.i686 openldap.i686 sane-backends-libs.i686 mesa-dri-drivers.i686 isdn4k-utils.i686 gsm.i686 gstreamer1-plugins-base.i686 lcms2.i686 mesa-libOSMesa.i686 libtiff.i686 gnutls.i686 nss-mdns.i686 mesa-libGLU.i686 mpg123-libs.i686 openal-soft.i686 sane-backends-devel.i686 libnsl.i686 libnsl.x86_64 gstreamer1.i686
3) Finally, follow the instructions provided by CodeWeavers for installation of the .rpm version of CrossOver.
That's it. I have only used this for Microsoft Office 365. It runs really well on the default Gnome desktop. One of the smoothest experiences I have had with CrossOver. No freezing, no fragmenting or pixelation; it just works.