1) make a WinXP bottle and copy the SimEasy binary to drive C
2) plug in your USB sim card reader
3) check dmesg for USB device name, should be something like:
[171602.701718] usb 1-1.2.4: Product: USB-Serial Controller
[171602.701722] usb 1-1.2.4: Manufacturer: Prolific Technology Inc.
[171602.703651] pl2303 1-1.2.4:1.0: pl2303 converter detected
[171602.705650] usb 1-1.2.4: pl2303 converter now attached to ttyUSB0
4) chown it to current user:
sudo chown $USERNAME /dev/ttyUSB0
5) make a symlink to provide the bottle with access to the device (as user, no sudo):
ln -s /dev/ttyUSB0 ~/.cxoffice/SIM\ toolkit/dosdevices/com1
That's it! You may run it or create a launcher.