1)Install the game using an unsupported game into a Windows XP bottle.
2)Follow suit with each of the expansions.
3)Download the critical rebuild file for the highest version installed, and run it when completed downloading.
http://files.bioware.com/neverwinternights/updates/windows/english/NWNEnglish1.69OrigUpdate.exe
http://files.bioware.com/neverwinternights/updates/windows/english/NWNEnglish1.69SoUUpdate.exe
http://files.bioware.com/neverwinternights/updates/windows/english/NWNEnglish1.69HotUUpdate.exe
4)Edit the bottle parameters -
Manage Bottles -> NWN Bottle -> Control Panel -> Wine Configuration -> Graphics -> Tick Emulate a Virtual Desktop, and set the resolution to what the fullscreen resolution you would like to be max. Other resolutions will appear as well in NWN.
5)Run the configuration utility. The rest should be self explanatory.
6)Play Game!