If you've used Games 8.1.x then you'll have an issue of a mouse bug that get really annoying when playing the game. The mouse only turns like 180º then it just wont turn any more.
Simple fix for in game: Open up Registry and add the key:
[Software\\Wine\\DirectInput] 1264890967
"MouseWarpOverride"="force"
or add that line to user.reg found inside your bottle.
This, unfortunately, stops the mouse working in the menus. To fix this add the key / add to User.reg:
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