If you find that you need to do a complete re-install (clean install) of CrossOver Games.
(Which will necessitate you creating new bottles and re-installing all your applications!)
I.e, you are completely deleting (un-installing) and then re-installing CrossOver Games.
Before you do the re-install of CrossOver Games, it is advisable to delete the CrossOver Games Preference file located at:
~/Library/Preferences/com.codeweavers.CrossOverGames.plist
Note that this refers to deleting and re-installing the entire application CrossOver Games, not any of the bottles or applications within CrossOver Games.