To play JA2 under Crossover, the only way that appears to work is to use the JA2 Stracciatella mod/launcher.
-Install via GOG installer into new Windows 10 64-Bit Bottle
-Don't launch the game yet
-Head to https://github.com/ja2-stracciatella/ja2-stracciatella
-Download and install JA2 Stracciatella
-Open JA2 Stracciatella, in the Data tab point the launcher into your installed folder eg 'C:\GOG Games\Jagged Alliance 2'
-Set desired graphics options
-Play
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