If the mouse DOESNT MOVE at the game menu, use this trick that was on a forum.
Click Programs->Run command, select the bottle with the game, enter 'regedit' and press run. Navigate to HKEY_CURRENT_USER/Software/Wine/, Create a key "DirectInput" (Edit->new->key), and in this key create a string value 'MouseHack', which you set to 'disable'. type in disable below the name of the value->click modify to do so.
Here is the link to the forum for references,
http://www.codeweavers.com/beta/cxmac/forum/?t=4;mhl=1970;msg=1958;forumcurPos=300#msg1970
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