Crusader Kings II Tips

Just played a 7 hour long session last night of this using Crossover 12, and it worked flawlessly with the following setup/wine tweaks: 

System specs: 

Fedora 17 x86_64, running kernel 3.6.9-2 
Intel Core i7 2600k, OC'ed to 4.4GHz 
16 GB DDR3 RAM 
128 GB SSD (game/OS install) 
1.5TB 5400RPM HDD (debug log pointed here) 
nVidia 660 GTX, 2 GB RAM, driver version 304.64-1 
    -- 1920x1080 resolution 
    -- Also acting as sound card, connected to monitor via HDMI 

Game settings: 

All expansions/DLC enabled 
Fullscreen @ 1920x1080 
Anti-aliasing set to 4x 

Wine Bottle: 

Installed via Steam into a bottle installed using the Civilization 5 CrossTie. 
Windows version changed in winecfg to be Windows 7. 
DX9 and DX10 native overrides installed 
Must use warn+heap debug logging
Emulate virtual desktop enabled
Launch using ck2game.exe rather than from Steam
Added/edited the following values to the registry under HKEY_CURRENT_USER -> Software -> Wine -> Direct3D: 
    -- DirectDrawRenderer (string) -> opengl (default, but I prefer having it explicitly defined) 
    -- StrictDrawOrdering (string) -> disabled 
    -- UseGLSL (string) -> enabled 
    -- Crossover was misidentifying my video card as an nVidia 8800 GT with 128MB RAM, so I added its properties to the registry in this location: 
         ** VideoMemorySize (string) -> your video cards memory size in MB. 
         ** VideoPciDeviceID (DWORD hex) -> Hex code for the device as provided by lspci 
         ** VideoPciVendorID (DWORD hex) -> Hex code for the vendor as provided by lspci