Tried this application with Crossover even though it said it was not known to work. Installed and started up fine. We're new to the app (lifelong Mac users who have never, ever used a PC) so we don't know if the functionality is 100% complete, but it works well enough that we could use a Driver scenario and start tooling around on a train. Throttle, braking, and other keyboard commands work fine, as do various onscreen buttons and functions.