I'm a missionary in Thailand raising my own financial support. I've been using TNTMPD for 2 years, on a Windows PC. The software is excellent for tracking supporters, and keeping tabs on donations. I rely on it entirely to manage relationships with about 200 people. I just bought a new Macbook (my first Mac) with Leopard OS and one of my biggest concerns was whether MPD would run on the Mac. Following Troy's excellent installation instructions, I successfully installed TnTMPD 2.0 r48 in CrossOver Mac 6.2.1, and easily imported my data from the PC. By putting an alias of my datafile on my Mac desktop, I can launch MPD with a single click on the alias, rather than having to launch CrossOver, and then launching MPD.
While none of this constitutes a full test, I can certainly recommend using MPD in CrossOver Mac.