Well, my ThumbsPlus bottle that worked perfectly on earlier versions does not work with this version. I cannot open the bottle. Instead, wineboot.exe uses 100% of a processor core and stays like that indefinitely. I tried it several times, including a 48 hour period, in the hope that it might sort itself out eventually. It didn't!
There is no clean exit either and I have to kill all wine* processes manually in order to restore my machine to a workable state.
When I have time, I will create a new bottle. But the fact that Crossover gets itself into such an unusable state by simply opening a bottle indicates there are serious issues with the current Crossover. 😷