I tried a basic windows xp bottle, directx9. Macbook Pro mid-2010, CX Games 10.1.
The DRM-free GOG version installed without a problem. Installer completed succesfully.
However, just running the witcher 2 start command shows up the launcher (I suppose) and then it disappears again. Nothing else.
cxlog gives this
** Thu May 19 22:51:46 2011
Starting '/Applications/CrossOver Games.app/Contents/SharedSupport/CrossOverGames/bin/wineloader' 'winewrapper.exe' '--workdir' '/Users/x/Library/Application Support/CrossOver Games/Bottles/THe Witcher/drive_c/Program Files/GOG.com/The Witcher 2' '--start' '--'
'/Users/x/Library/Application Support/CrossOver Games/Bottles/THe Witcher/drive_c/Program Files/GOG.com/The Witcher 2/Launcher.exe'
fixme:advapi:SetEntriesInAclA 1 0x33f764 0x0 0x33f79c
fixme:advapi:SetSecurityInfo stub
fixme:advapi:SetEntriesInAclA 1 0x33f750 0x0 0x33f798
fixme:advapi:SetSecurityInfo stub
fixme:advapi:SetEntriesInAclA 1 0x33f770 0x0 0x33f7b8
fixme:advapi:SetSecurityInfo stub
fixme:exec:SHELL_execute flags ignored: 0x00000100
fixme:heap:HeapSetInformation 0x0 1 0x0 0