Ubuntu 12.04 64bit Nvidia 560Ti.
The game runs flawlessly in high detail (virtual desktop 1440x900). Mods work fine as well(I am using SkyUI). I would give it a gold if it were not some minor issues:
-Controller is not supported
-Tab Key sometimes locksout and is not detected as pressed. This is not really problem as you usually access the
skills,map,inventory screens from their hotkeys anyway.
-Graphical glitches/screen blank when underwater(just noticed that and I am not sure if it happens all the time).
Other than that the game runs very smoothly as if in native with no other issues.