Hi
This concerns Skyrim Anniversary edition played on a MacBook Pro M1.
It has already been said that DXVK backend should be disabled.
To go a little further, I tried the advice given on this page : https://www.reddit.com/r/macgaming/comments/qt4e1b/you_can_run_the_latest_dxvk_with_crossover_on_mac/
I can now play Skyrim at 1440x900 with antialiasing set on low, and object fade set to maximum. The texture glitches have completely disappeared (I mean completely, not even appearing here and there like before).
I can't measure the framerate but I guess it is around 30/40 FPS, only dropping at times (when in vast open areas mostly).
Hope this helps someone.