I've managed to install and get the game to launch under crossover Mac 11.2.2.
I installed the game by installing the Wizards 101 crosstie and then installing the Pirates 101 game into the same bottle. After installing the game crashed on first launch - but if you close the app after the crash and re-launch. Then open the settings and turn off the full screen option.
I went through the tutorial after that without a problem.
I need to play more before I can rank the game but so far I have not seen a single problem after the initial crash.