I installed this from a cd in 10.0 and 10.3 but it would not work(parts of the screen we blank) I appears to work fine in 11. I have not finished the game but the cutaway scenes, the object search screen(was missing the list previously) and the puzzles are working as far as I can tell.
I also tested it in a clean Big Fish games bottle(bottle installed via CrossTie with the additional files the tie installs) and it was working fine there as well.
One last bit of info. I am running Ubuntu 11.10. The Crossover that is available in the Software center is fairly outdated, 10.0.1 I believe. So you will have to use the current .deb file on Crossovers website.