Until a specific Path of Exile 2 forum is created, just wanted to write down this workaround for POE2 that may help some of you.
By default, POE2 is not working with Crossover or Crossover Preview. But you only need to manually edit a configuration file to fix this.
First of all, install POE2, either from the executable you download from the official site or via Steam (you can create a Steam bottle, of course). Then launch the game; it will crash but it will create the necessary folders in your drive before exiting.
You then navigate to '/Users/[YOUR NAME]/Documents/My Games/Path of Exile 2/' and edit the file poe2_production_Config.ini to change renderer_type=Vulkan to renderer_type=DirectX12.
Save the file and relaunch POE2.
I'm using D3DMetal, MSync and High Resolution mode (Crossover Preview) on Mac M1 and the game runs smoothly so far.