I've run PaperPort 11 under Windows XP, and noted Germike's Tip about PaperPort not running under Windows 98. Based on the System Requirements that Nuance shows, it isn't surprising that PaperPort 11 won't run under CrossOver in a Windows 98 bottle, but unclear why it hasn't run in a Windows 2000 or XP bottle.
System Requirements also include Microsoft Internet Explorer 5.5 or higher, so I'm testing to see whether I can run PaperPort 11 under CrossOver for Mac 10.0.1 if I first install Internet Explorer into that bottle. I've tried IE versions 8 and 7 (which is a supported application), but haven't been able to run PaperPort.