I thought I'd write a thread about what I saw when I tried to run OnLive. If anyone has any additional info, feel free to post here.
With Crossover I can't get it to connect at all. Each time I launch the application, it just says "Unable to contact the OnLive Game Service."
With Wine(1.4) however, I get it to work somehow. It works pretty well in fact, except for the little fact that you cannot use your mouse in-game. It works fine in the menus but in-game mouse movement or button clicks don't seem to have any effect. If the game can be controlled only by using keyboard, it's playable.
EDIT: I just noticed I was still using Crossover Games 10.3, updated to 11.0.1 and now it does the same as in plain wine, so the mouse issue purely a wine probleḿ.