My experience with installing Noteworthy with Crossover 6.2 and Mac OS 10.5.2 was an error message on first run that Noteworthy could not find the font nwcv15.ttf (which was, in fact, installed in the c:\windows\fonts folder in the bottle containing Noteworthy). Quitting Crossover and restarting it solved the problem. Beyond this, the only problem I have encountered so far is in getting Noteworthy to recognize an external USB keyboard; I suspect appropriate windows drivers for the keyboard are the problem.