I purchased Neverwinter Nights - Diamond from GOG.com and installed it into a Windows XP bottle using Crossover Games for Mac 10.1. Computer is a Mac Pro, 2 x dual-core 2.66 GHz Xeon CPUs, NVIDIA GeForce 7300 GT GPU, 8 GB RAM, Mac OS 10.6.7.
The installation ran smoothly. I downloaded the files setup_nwn.diamond.exe, setup_nwn_diamond-1.bin and setup_nwn_diamond-2.bin from GOG.com into a single folder and selected setup_nwn.diamond.exe as the installer file for Crossover Games.
The NWN start-up splash screens and animation do not display; the screen is white. The sound can be heard, however, and repeatedly pressing Esc will skip each splash screen until the game menu is reached.
The game plays well, with one frustrating exception; the game screen will occasionally go black or grey during play. This problem has been reported by others in previous versions of Crossover Games. The game interface can still be called using the keyboard when this happens and the game can be paused and saved. Re-loading a saved game returns the screen to normal. I have not been able to determine a trigger for the screen blanking. I have observed it both during play and while the game is left idle, which I purposely did for several minutes until the problem happened. I have not been able to find a video configuration in the game that makes the problem better or worse.
Strangely, I have experienced this exact same problem happens with the Mac version 1.69 of NWN. The Mac version is Power PC code, having never been made Universal Binary for Intel CPU Macs, which may be a cause.
The game will allow access to online multiplayer, but I have not tested this in actual play yet.