I'ved played NWN 2 several weeks on Crossover Games 7.1 to 7.1.2 on Mandriva Linux 64bit.
It mostly work fine, only a graphic problem on the lower left corner (1/4 of the screen), i'ved only see the ground textures (no houses, persons etc.). Some crashes (very seldom) of the game i'ved also noticed...
I think, the next few day I'll try it again with 7.2 and hope i can go further on the game (I'ved stoped playing after a bug, where I cannot leave the screen).