I'm trying out Crossover Office on Ubuntu 7.10 Gutsy. Excel and Powerpoint will open files that are stored on NFS/SAMBA. Word would not, and would hang until I killed it. These files lived on "drive Z", my root directory. Files actually on my hard drive would open ok, but not on directories that were mounted via NFS or SAMBA (I tried both).
I found this tip in the FAQ:
4.1.10. Office won't let me save files on NFS filesystems!
This is known to happen with Word 97 but may happen with other Microsoft Office applications too. The solution is to run the following command:
$ ~/cxoffice/bin/regedit --bottle bottlename - <<EOF
[HKEY_LOCAL_MACHINE\Software\Wine\Drives]
"x:"="hd"
EOF
Where 'x:' is the drive which is located on the NFS filesystem. For instance if your home directory is on NFS then you would replace 'x:' with 'c:'.
As suggested, I ran regedit, but there was no entry for drive Z. I added one for "Z:" and set it to "hd". Everything seems to work now.