Installed from retail CD, circumvented the problem with not being able to see the CD drive, and runs without issue. All sounds appear to be there, Mirrors work fine, have everything turned up to full graphics. A little bit of slowdown in the scene at the warehouse after the Prologue, but I did have post processing effects on full, so it must have been the rain causing it, so a little trial and error with the video settings.
Running on Crossover Games 10.1.0, on Mac OSX 10.5.8