I have Matlab R2006a running perfectly (as near as I can tell) under CXOffice 6.1.0.
Other users explain how at:
http://appdb.winehq.org/appview.php?iVersionId=5385&iTestingId=5290
Note: I had to setup a .windows-serial file and copy the serial number from my Matlab license.dat file here. Setting up this file is explained:
http://www.codeweavers.com/support/docs/crossover-standard/advanced-config
Good luck!