Tested on a Mac Mini Core 2 Duo 1.83 Ghz, OSX 10.5.3, and the test drive version of CrossOver Games 7.
It installs and runs directly from the Gold edition CD (published by Strategy First) without tweaking of any sort. The official 1.12 patch also installs correctly if run within the same bottle.
The game runs with more than adequate performance in the starting sectors and all functionality is enabled, including key shortcuts, sound and videos. Had one crash while saving the game (it did generate a save file, but it crashed before completing it and became corrupted), but none in subsequent saves.The community 1.13 patch adds one strange issue in which the OSX cursor overlaps with the Jagged Alliance 2 one. This issue was not present in the unpatched or 1.12 official StrategyFirst versions. All other functionality of the community patch works as intended.
The only performance hit noticed is a noticeably slower tracking of fired shots compared to a Windows machine of similar hardware setup running Windows XP 64-bit edition.