The first problem I noticed was that not all of the UI elements were being displayed correctly. As far as I know, there is no fix available yet for this. The second problem was getting access to the iTunes store. When clicking the the iTunes Store button, the whole UI freezes, and I am unable to do anything, being forced to end the iTunes process. I am not sure if this is caused by my low amount of RAM (512mb) or because the iTunes store isn't supported in CrossOver. Other than that, iTunes 10 worked great! The music played flawlessly, I could create playlists, add songs to the library, delete them, etc...