Tested on:
iMac 2.7 GHz Intel Core 5
12 GB Ram
AMD Radeon HD 6770M 512 MB
OS X 10.7.3
On crossover version 11
The game starts and seems to run fine. However, when going to the Introduction in the tutorial section, the game crashes with E1222: Out of memory. I'm able to reproduce this error by following the same steps. I have not given up, but have not been able to resolve this issue so far.