Aside from the general issues (occasional crashes, and the litany of error messages when the game first begins (all of which can be safely ignored)), things have been fairly smooth--but I did want to start collecting repeatable issues so that if anyone figures out a fix, we can share it with the world.
The most frustrating one for me is the Civilization Manager bug--while it sometimes works, clicking the "Civilization Manager" tab will usually cause the game to crash.
This is in CXG 9.2, with an Intel MacBook running Snow Leopard and using an Intel GMA950 with 2GB RAM.