It took me awhile to figure everything out, this is to do with mouse movement but will also address all issues
Insert disk and install into a windows 2000 bottle
Don't start it yet because it won't work
Download Killap's restoration Project(includes patch)
http://www.nma-fallout.com/forum/viewtopic.php?t=40443
The download link is located in his signature on the right hand side
download the installer, not the manual
Copy to your fallout 2 folder
Set the bottle containing fallout 2 to your default bottle in the manage bottles screen
Double click on Killap's RP and install everything into the directory(should find it automatically)
Alternately you can install other patches or megamods but I've heard this the best
and most stable for playing, no need to install the official patch because Killap's patch
addresses all the issues, (at least thats what I read on peoples posts)
Then Open up the manage bottles screen
Click on the Fallout bottle and go to the control panel button on the top right menu bar
Click on Winecfg and click launch
Click on libraries on the top menu bar
Paste "ddraw.dll" and click add,then click yes to the warning about order
Then launch fallout and it should work grand
I'm no expert in computers, I just searched the net over and gathered all this info and it worked for me, mods and patches can be found at:
http://www.nma-fallout.com/forum/dload.php?action=category&cat_id=19
Sfall is included in killap's RP and this will sort out the mouse movement problem
If you don't want to clutter your fallout bottle then create a new winxp bottle and set that to default in
the manage bottles menu
adios amigos