I've been using CrossOver to run Everquest on a 27" iMac for a couple of years; access to the big screen is a big win for this combo. Recently I have also bought an Alienware Alpha with a cheap 24" Benco HDMI monitor to compare.
With CrossOver I have become used to request crashes when moving in areas of high population density - Guild Lobby, Plane of Knowledge. I don't dare go near a raid, and have to choose my paths carefully. Similar crashes happen even in low density zones with a lot of graphics objects (Valley of Lunanyn, etc) after a time, and after a number of zonings. Following is erratic. Switching between instances is a little faster on the Alpha as well.
I should say that I also get crashes on the Alpha, but one a month, not 4-5 an hour. Running on the Alpha saves me about 15 minutes doing daily quests on four characters over 90 minutes.
One criticism I have on CrossOver 14 is that the menu option to launch apps was dropped, replaced by a window with icons. This adds an extra step (search and click) to relaunching after crashes, and was a major regression for me. I did bug report it during beta, but it was cancelled.
Conclusion: if you need to run Everquest on a Mac, CrossOver still works, probably better than 80% quality (lets call it somewhere between Bronze and Silver). For many uses the problems that exist can be lived with; but for many common uses, it will still be a struggle.