I'm reposting in this forum Meredith's post from elsewhere, just so it can be found here too:
Meredith writes:
Hi there,
[Elden Ring] will not work, as it is a DirectX 12 game and it uses EAC. Please see this blog post for more info about our plans for DirectX 12 support.
Best,
Meredith
PS from me: DirectX 12 may come for Mac as soon as CrossOver 23. EAC is Easy Anti-Cheat, which might be able to worked around for offline play at least.