It took me about a day to get it working, and maybe 2 hours of actual time if you don't count downloads.
*) I purchased an online copy, downloaded the downloader app, and then had to run it on an XP machine to snag the install files. I couldn't figure out a way to get the downloader to work, but then again I didn't try very hard either.
) Downloaded & installed the trial copy of Crossover Games.
) Downloaded & installed the Apple Dev Tools (to get make, gcc, etc.)
) Downloaded, compiled, and installed the Mono/GMCS package.
) Downloaded, compiled & installed the LOTRLinux client. (Required?)
) Downloaded & installed the LOTR Mac Client.
) Installed the DDO game from a 2000 bottle. Hung on .NET at the end, and I canceled out.
) Did the regedit hack for .NET. (Which I now believe I didn't need to do. I should have done this before the install if I cared.)
) Signed up for a DDO account using my SN.
) Downloaded a LOTR patch replacement dll, found on their forums at this site, and moved it to my DDO installation, with a new name.
) Started the LOTRMac Client and Did a Tools->Patch. It hung after awhile and I force quit it. This got me past a dll error message.
*) Created a simple replacement UserPreferences.ini in my '~HOME/Documents/Dungeons and Dragons Online'. A search found this on the DDO forums. This got me past the "131" error. This resets my sound options to mute, but those settings can be changed via 'Options' in game.
*) Started up, watched the movie, and was presented with character creation screen.
I have no idea about performance yet.
Thanks Alan & Walter. Your posts contained all of the pointers I needed.