Doom 3 runs pretty good, just as good as Prey does. This is probably because both games use the same engine.
But... because of the same engine, they also have the same faults. Both games have random crashes, usually after 5-10min of gameplay, which pretty much makes the game unplayable when you need to restart the game so often, and sorry for you if you don't quicksave every 3rd second.
Since it's already so good optimized and all that, it's a shame it's not running stable. I can only wish this will get fixed.