I recently installed D2R on a Macbook Pro M1 (Apple Silicon). It works really well, but I get graphics artifacts in some of the areas in the game. Specifically the river of flame in act 4 displays big white rectangles in many places making the game unplayable there. My current solution is to switch to original gfx in that area. If I could change some settings to make it go away it would be very nice.
Best, Marc