Did a Full Install into a new bottle. Did not opt to downgrade Direct X. Turned on "Emulate a virtual desktop" in winecfg afterwards.
Game works and runs as it should, mostly. The problem is that parts of the screen flickers and often disappears. This is usually the static parts, while "active" parts, like character animations or selectable choices remain visible. This annoying invisibility will make it hard to find evidence on the screen but otherwise the game is playable.