MacOsx 10.5.7
Crossover Games 7.2.2
Install the game in a xp bottle;
Download this file :http://www.microsoft.com/downloads/details.aspx?FamilyID=28494391-052b-42ff-9674-f752bdca9582&Di
splayLang=en#filelist and install it in the bottle of civIV.
Then this part: Confront DRM issues (link to http://www.codeweavers.com/support/wiki/dmca)
May you encouter problems in the game (wich i didnt) than you can try the install of this update:
http://www.firaxis.com/games/downloads.php
Note: when starting the game there are some notifications that the game wouldnt not run with this configuration, you can just ignore that by clicking "ok", because it runs properly.
Have Fun!
Paul The Tall