I noticed that my retail copy of Bioshock installs as v1.0, so I figured I'd try patching it up to 1.1 with the executable from http://www.2kgames.com/bioshock/support/
The launcher starts properly, gives me a warning that it should only be used on vanilla Bioshock installations, and then launches a dialog saying that it's searching for installed engines (or something like that), but the progress bars never leave 0%; the dialog just sits there indefinitely. The "cancel" button still works.
This is in cxgames 9.1.0. Anyone else have any luck installing the 1.1 patch?