Ok, this Bioshock2 runs with cxgames 10, if one uses the bioshock2 version of games for windows live fake xlive.dll, see:
http://appdb.winehq.org/objectManager.php?sClass=version&iId=19342
That is, I can run the game, adjust the options, redefine controls, start a new game... But, when the new game has loaded, it asks to press space to continue, but the keyboard input is lost :(
The same issue happens with wine 1.3.14, see:
http://bugs.winehq.org/show_bug.cgi?id=26269
Any tips or tricks I could try? This is soooo close...