Bejeweled Twist 1.0 installed and ran flawlessly under Fedora 8 using Crossover Games. The only shortcoming was that it didn't allow me to use either of its higher-resolution settings, 1024x768 or 1920x1200, for lack of 3D acceleration. Perhaps if I had gotten a bit more ambitious with my choice of graphics drivers even that objection would have been overcome. At any rate, I have absolutely no complaint about its performance, and I suspect that most, if not all, games using the PopCap framework should be similarly effective.
At some point, I may try it in an alternate distro I run, namely Ubuntu 9.04 amd64. It'll be interesting to see if it runs as well there.