I ran into 2 problems trying to make AC work in crossover 11.
1) The launcher crashes immediately. This is because AC needs Internet Explorer 7 installed in the same bottle.
2) After patching you get a black screen after selecting your character. If you wait the network connection will timeout. This seems to be because Wine is now more strict with network ports. To fix go into UserPreferences.ini in Documents/Asheron's Call and edit the Net section to look like the following:
[Net]
ComputeUniquePort=False
BindInterface=
UserSpecifiedPort=9000
After these changes the game runs well.