My understanding is that unfortunately CrossOver is not designed to interface with hardware, only software. If you search the forums for USB, you will find that USB device support is an issue. There are a few posts about getting some sort of USB to Serial working and/or doing symbolic linking at the OS level that may work (you might want to start here to explore this).
Please Note: This Forum is for non-application specific questions relating to installation/configuration of CrossOver. All application-specific posts to this Forum will be moved to their appropriate Compatibility Center Forum.
CrossOver Forums: the place to discuss running Windows applications on Mac and Linux
CodeWeavers or its third-party tools process personal data (e.g. browsing data or IP addresses) and use cookies or other identifiers, which are necessary for its functioning and required to achieve the purposes illustrated in our Privacy Policy. You accept the use of cookies or other identifiers by clicking the Acknowledge button.