Install Abe's Oddysee into a 32-bit Windows 10 Bottle.
Download and install the latest legacy version of "DXGL" from here - https://dxgl.org/Downloads/ into the same bottle.
Once DXGL is installed, run it.
Choose or "add" the AbeWin.exe, and then apply Abe's custom resolution settings within DXGL - 640x480x8... and make sure to apply 16-bit colour mode!
You can now run Abe in full-screen mode, or windowed and resizable.